+30 69 51 68 16 26    info@crossbees.com


The first successful, homologous insemination occurred in 1790 in Scotland, whereas the first heterologous insemination occurred in 1884. For the first time, the sperm of a donor (in this case a student of medicine) was injected into the uterus of a woman.

Dr. Steptoe and Dr. Edwards went a step further and developed fertilization in vitro. In this manner, the first “tube baby”, Louise Brown, was achieved in 1978 with a follicle that was taken for the natural cycle, fertilized and then re-inserted.

At that time, this method was thought to be for women with obstructed oviducts. Nowadays, IVF is considered a standard treatment.

In a classic IVF, the ovaries are stimulated with drugs in order to provoke a “superovulation”. The oocytes are taken during a brief intervention and are fertilized in the laboratory by the sperm of the partner or donor. After three or five days, the resulting embryos are implanted in the uterus; the remaining embryos can be vitrified. This method is the basis for several treatments, including pre-implantation diagnosis and the preservation of fertility. 

Follicles are aspired. Not every one of them contains an oocyte, and not every oocyte is mature. Thus, the exact number of oocytes can be determined only after an ovum pick up (OPU). 

The sperm of the partner is directly injected in the oocyte in the laboratory. The oocyte is 80 times bigger than the sperm. After 12–14 hours, the embryologist can see whether fertilization has been achieved. 

Graphische Darstellung der IVF Behandlung

How to get to our offices

CROSSBEES™ offers healthcare consultancy services to those seeking treatment and to clinics offering it and in this website, we have put together some basics around infertility and the legislative environment around Europe.


We aim to contribute both to Infertility Treatment and Fertility Planning and to make a difference for future generations by providing education and disseminating information.

Contact us

48 Themistokli Dervi Avenue 
Athienitis Centennial Building
1066 Nicosia, Cyprus
Tel. +30 69 51 68 16 26
Email: info@crossbees.com

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